TK data gets thrown into reports as a table and a figure. It rarely gets treated as what it actually is — one of the most powerful interpretive tools in your nonclinical program. TK underpins every dose justification and exposure margin calculation you make. Get it right and your NOAEL is bulletproof. Get it wrong and your entire tox package starts to unravel. This issue breaks down the good, the bad, and the ugly of TK profiles.
Dessi McEntee
Mar 194 min read
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